News

University of Barcelona second centre to start clinical trial on decellularized homografts for aortic valve replacement

A team of surgeons at the Hospital Clínic de Barcelona, led by Dr. Eduard Quintana (MD, PhD, FETCS), successfully performed the first implantation of a decellularized aortic homograft for aortic valve replacement in Spain. The... [more]

3rd ARISE Steering Committee Meeting / Study start at second clinical centre upcoming

Members of the ARISE Steering Committee met in Venice on the 18th and 19th of March 2016 and discussed progress within the ARISE project, which focuses on decellularized homografts for aortic valve replacement. Within the... [more]

New study on decellularized aortic homografts for aortic valve and aorta ascendens replacement published

Researchers from Hannover Medical School/Germany and the University Hospital in Chisinau/Moldavia have published the early results of decellularized aortic homografts (DAH) for aortic valve replacement (AVR) in February 2016... [more]

Welcome to ARISE

65,000 aortic valve replacements (AVR) are performed in Europe each year to treat acquired and congenital aortic valve diseases. Current AVR options are, however, limited for young patients - especially female patients - and those unwilling to accept life-long medical anticoagulation with its inherent risks. None of the currently available prostheses for AVR is tailored toward the individual patient or allows for individual regeneration. The ARISE project will bridge this therapeutic gap in a clinical study to determine the feasibility, safety and efficacy of regenerative heart valves for aortic valve replacement.